What Is The Difference Between Norepinephrine and Epinephrine?
TheJDocRealMinute TheJDocRealMinute
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 Published On Mar 28, 2021

#functionalmedicine #epinephrine #chiropractic

Epinephrine and norepinephrine are very similar neurotransmitters and hormones. Epinephrine has slightly more of an effect on your heart, while norepinephrine has more of an effect on your blood vessels.

Epinephrine and norepinephrine are two neurotransmitters that also serve as hormones, and they belong to a class of compounds known as catecholamines.

As hormones, they influence different parts of your body and stimulate your central nervous system. Having too much or too little of either can have noticeable effects on your health.

Chemically, epinephrine and norepinephrine are very similar. Both epinephrine and norepinephrine work on alpha and beta receptors. However, epinephrine has a greater effect on beta receptors compared with norepinephrine.

Alpha receptors are only found in the arteries. Beta receptors are in the heart, lungs, and arteries of skeletal muscles. It’s this distinction that causes epinephrine and norepinephrine to have slightly different functions.

What are their functions?
Epinephrine
Epinephrine, also called adrenaline, has powerful effects on the body. These include:

increased blood sugar levels
increased heart rate
increased contractility (how hard the heart squeezes)
relaxation of smooth muscle in the airways to improve breathing
These effects are designed to give your body extra energy. When you’re very stressed or afraid, your body releases a flood of epinephrine. This is known as the fight-or-flight response, or adrenaline rush.

Norepinephrine
Norepinephrine, also called noradrenaline, has effects similar to those of epinephrine, such as:

increased blood sugar levels
increased heart rate
increased contractility
Norepinephrine can also cause your blood vessels to narrow, which increases blood pressure.

The main difference
Both epinephrine and norepinephrine can affect your heart, blood sugar levels, and blood vessels. However, norepinephrine can also make your blood vessels become narrower, increasing blood pressure.


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