MIT 6.874/6.802/20.390/20.490/HST.506 Spring 2021 Prof. Manolis Kellis
Deep Learning in the Life Sciences / Computational Systems Biology
Playlist:    • MIT Deep Learning in Life Sciences - ...  
Latest slides and course today: http://compbio.mit.edu/6874
Spring 2021 slides and materials: http://mit6874.github.io/

00:00 Review
04:30 Linear mixed models
13:10 Heritability
16:02 Defining hg2
20:21 Stratified LD score regression
41:20 Application to chromatin and gene expression data
52:36 Decomposition of genetic associations
1:05:15 Experiments of nature
1:09:57 Polygenic risk models