MIT 6.874/6.802/20.390/20.490/HST.506 Spring 2021 Prof. Manolis Kellis
Guest lecture: Wengong Jin
Deep Learning in the Life Sciences / Computational Systems Biology
Playlist:    • MIT Deep Learning in Life Sciences - ...  
Latest slides and course today: http://compbio.mit.edu/6874
Spring 2021 slides and materials: http://mit6874.github.io/


0:00 Introduction
1:16 Drug discovery
3:57 Computational drug discovery
17:14 Deep learning
22:27 Antibiotic discovery
26:30 Traditional approaches
30:16 Antibiotic discovery using GNNs
47:32 Biology aware models
54:35 Incorporating biology and chemistry
1:05:54 De novo drug design
1:06:57 Graph generation
1:13:51 Junction tree variational autoencoder
1:25:03 Conclusion