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► THIS VIDEO will be a comprehensive lecture on disorders of the red cell, specifically tailored for medicine students. 🩸📚 In this informative session, you'll gain valuable insights into various aspects of red cell disorders, including their prevalence, causes, and classification. 📊💉

Red cell disorders are among the most prevalent medical conditions worldwide, and understanding them is crucial for medical professionals. Anemia, which can result from factors like iron deficiency, haemoglobinopathy, and chronic infection, will be explored in depth. 🔍🦠

The lecture delves into haemolytic anaemia, where the lifespan of red cells is shortened, and polycythemia, which can result from myeloproliferative diseases or hypoxia-induced responses. 📈🩹

We'll start by examining the structure of red cells, their origin from erythroblasts in the bone marrow, and their vital role in oxygen transport. The video explains how erythropoietin regulates their production and highlights the lack of a nucleus in red cells, limiting their lifespan to approximately 120 days. 🏥🩺

Anemia is a widespread condition, but its definition must consider factors like the patient's age and gender. A detailed table illustrates typical haemoglobin concentrations at different ages, emphasizing gender-specific differences. 💡👩‍⚕️👨‍⚕️

The lecture covers common symptoms of anemia, including fatigue, shortness of breath, poor concentration, palpitations, and pallor. 🤕❗️

To classify anemia effectively, we will explore the analysis of red cell volume. The lecture provides a comprehensive overview of microcytic hypochromic, normocytic normochromic, and macrocytic anemias, along with their subtypes. 📉🔬

The focus then shifts to iron deficiency, its physiology within the body, and the importance of regulating iron intake. 💪🌾 The video discusses how iron is predominantly utilized for the production of hemoglobin and takes you through the intricate process of hemoglobin synthesis. 🌡️🔨

Iron deficiency, a widespread issue, can result from various causes, such as chronic blood loss and gastrointestinal conditions. 🩸🔍 It also emphasizes the importance of investigating gastrointestinal causes in non-menstruating individuals. 🚺🚹

Treatment options for iron deficiency, including oral and intravenous iron supplementation, are explained, and the lecture features a real-life blood film to illustrate iron deficiency characteristics. 📋💊

► RELATED VIDEOS - If you liked this video and need some more information about the subject, you’ll probably want to check the following videos out:
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Disclaimer: Lecturio offers educational content for healthcare students to prepare for exams and/or to review knowledge gained at a Medical School. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment suggestions. Our resources are strictly for educational purposes. Always consult healthcare professionals for medical concerns.

► THE PROF 👨‍🏫
Your lecturer is Prof. Paul Moss. He is Professor of Hematology and Head of the School of Cancer Sciences at the University of Birmingham. He studied Medical Science at the University of Cambridge. Later on he was a fellow of the Royal College of Pathologists. His research is primarily focused on cancer cell biology, clinical trials and tumor immunology. 🩺

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Chapters:
00:00 The Red Cell Structure, Production and Function
00:33 Understanding Anemia
00:43 Factors Affecting Hemoglobin Levels
02:06 Symptoms of Anemia
02:35 Classification of Anemia
02:40 Microcytic Hypochromic Anemia
03:06 Normocytic Normochromic Anemia
03:20 Macrocytic Anemia
03:43 Iron Deficiency and Its Physiology
04:28 Iron Utilization in Hemoglobin Synthesis
04:51 Iron Regulation
06:00 Heme Biosynthesis within the Immature Red Cell
07:31 Causes of Iron Deficiency
08:47 Treating Iron Deficiency
09:13 Identifying Iron Deficiency on a Blood Film