A six-year-old is showing the symptoms of puberty and the team tries to determine whether the cause is genetic or environmental. Guest starring Bailee Madison.

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From Season 3 Episode 19 ''Act Your Age'': A six-year-old girl suffers ailments expected in much older patients. Tensions mount between Chase and Cameron, leading House to intentionally assign them to the same tasks, including investigating the young girl's home, where they find something possibly incriminating on the girl's father.

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