House attempts to diagnose a young boy whose grandfather is convinced that he is possessed. The only way to prove this diagnosis is via exorcism.

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From Season 8 Episode 18 ''Body and Soul'': A boy (Riley Lennon Nice) is admitted to the hospital after nightmares about being choked led to breathing problems. His mother tries to balance the medical diagnoses of the team with the boy's grandfather's belief that he is possessed. Meanwhile, Chase and Park debate the meaning of their sex dreams, Dominika discovers House's deception, and Wilson tells House that he has cancer (Stage 2 Thymoma).

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