Sickle Cell (Hemoglobin SS) Disease: Acute & Chronic Presentation | Pediatrics
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 Published On Jan 28, 2024

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► THIS VIDEO will give you a comprehensive overview of Hemoglobin SS Disease, a classic presentation of sickle cell disease. 🩸💊
One of the key aspects to understand is the vaso-occlusive pain crisis, a common occurrence in patients with hemoglobin SS disease. These individuals often experience excruciating pain, often requiring high doses of morphine for relief. However, this can lead to potential addiction issues, making it crucial to differentiate between pain crises and non-pain crises. 🤕💉
Moreover, individuals with sickle cell disease are at an increased risk of stroke, even in childhood. The sickled cells can cause microvascular trauma, triggering a hypercoagulable cascade, emphasizing the importance of identifying such patients. 🧠❌
Additionally, Hemoglobin SS Disease can lead to complications such as splenic sequestration, acute chest syndrome, myocardial dysfunction, priapism, aplastic crisis, and osteomyelitis. These complications can be life-threatening and challenging to manage. 🏥🚨
Patients may also develop chronic conditions like avascular necrosis of joints, cholecystitis, hearing loss, leg ulcers, retinopathy, renal failure, liver cirrhosis, and pulmonary hypertension over time. Understanding these potential complications is essential for medical students and healthcare professionals. 📚👩‍⚕️👨‍⚕️

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► THE PROF 👨‍🏫
Your tutor is Brian Alverson, MD. He is the Director for the Division of Pediatric Hospital Medicine at Hasbro Children's Hospital and Associate Professor of Pediatrics at Brown University in Providence, RI. He has been active in pediatric education and research for 15 years and has won over 25 teaching awards at two Ivy League Medical Schools. Dr. Alverson has extensive experience in preparing students for the USMLE exams and has test writing experience as well. 🩺

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Chapters:
00:00 Understanding Hemoglobin SS Disease
00:09 Vaso-Occlusive Pain Crisis and Addiction Challenges
00:39 Increased Risk of Stroke
00:57 Splenic Complications
01:15 Acute Chest Syndrome
01:33 Myocardial Dysfunction and Priapism
01:54 Aplastic Crisis
02:07 Osteomyelitis and Salmonella Osteomyelitis Risk
02:40 Chronic Complications
03:20 Study Smarter, Not Harder with Lecturio

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