Phentermine is an FDA approved oral therapy that assists in short-term weight loss in combination with diet and exercise. Phentermine belongs to the appetite suppressing family and is a weak relative of amphetamine. Phentermine may be appropriate when the BMI – body mass index – exceeds 30 or 27 in the presence of other cardiovascular risk factors .

Phentermine is inappropriate for those who desire to lose a few pounds. In selected individuals it should be administered on hour or two before or after breakfast. A split dose of 18.75 mg before breakfast and dinner is also acceptable. Since phentermine functions as a stimulant, a bedtime dose risks insomnia.

Therapy may continue for a maximum of 12 weeks. Unfortunately a regain of weight generally occurs in the absence of a continuous low calorie diet. weight regain occurs after discontinuation of therapy. The greatest weight loss occurs in the first several weeks of therapy. Effectiveness of Phentermine is lost beyond 12 weeks of use.

Contraindications against use of phentermine include coronary artery disease, arrhythmia, uncontrolled blood pressure and heart failure. Hyperthyroidism, glaucoma, an agitated state and pregnancy also exclude Phentermine eligibility. Phentermine should not be prescribed to those with a history of drug abuse.

Generally well tolerated, adverse effects of phentermine include dry mouth, unpleasant taste, diarrhea or constipation. Hives or urticaria, hair loss and erectile dysfunction may also develop. Symptoms of acute phentermine overdose present as restlessness, tremor, panic attacks, confusion and hallucinations. Insomnia, irritability, hyperactivity and psychosis reminiscent of schizophrenia may indicate chronic toxicity.