The Vicious 6 are the main antagonistic faction of Illumination's Minions: The Rise of Gru. They are a group of 6 villains that operated in the 1970s founded by Wild Knuckles, and established a reputation for being the most powerful villains of the decade.

Synopsis:
In the 1970s, young Gru tries to join a group of supervillains called the Vicious 6 after they oust their leader -- the legendary fighter Wild Knuckles. When the interview turns disastrous, Gru and his Minions go on the run with the Vicious 6 hot on their tails. Luckily, he finds an unlikely source for guidance -- Wild Knuckles himself -- and soon discovers that even bad guys need a little help from their friends.