Persistent depressive disorder (PDD), previously known as Dysthymia, and often called High Functioning Depression is a mood disorder consisting of similar cognitive and physical problems as depression (major depressive disorder), but with longer-lasting symptoms. The concept was coined by Robert Spitzer as a replacement for the term "depressive personality" in the late 1970s.

In the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV), dysthymia is a serious state of chronic depression, which persists for at least two years (one year for children and adolescents). Dysthymia is less acute than major depressive disorder, but not necessarily less severe.

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