In 1999 a landmark Space Shuttle mission came close to suffering a fatal mishap after a gold pin damaged one of the engines and made the shuttle run out of propellant early. However it could have been much worse....

Further info from Wayne Hale's blog post on the subject.
https://waynehale.wordpress.com/2014/...

STS-93 was the first mission commanded by a woman - Eileen Collins, and also carried the heaviest payload of any shuttle launch.