sulfonylureas pharmacology, diabetic drugs pharmacology, clinical pharmacology lectures, antidiabetic drugs pharmacology

📍 Sulfonylureas are known as insulin secretagogues. They work by stimulating insulin secretion from the pancreatic beta cells, to decrease post-prandial blood glucose. Sulfonylureas is a class of medications, that may be prescribed to treat people with type 2 diabetes. The sulfonylureas most commonly used in clinical practice are the second-generation drugs, 📍 such as glyburide, glipizide, glimepiride, and sometime tolbutamide.
Side effects of sulfonylureas include hypoglycemia, hyper-insulinemia, nausea, and weight gain. They should be used with caution in hepatic or renal insufficiency, because accumulation of sulfonylureas may cause hypoglycemia.
📍 Sulfonylureas contraindications include: severe cardiovascular comorbidity, Obesity, Severe renal or liver failure and Sulfonamide allergy.
📍 Talking about drug interaction of sulfonylureas: concomitant use with Biguanides may be associated with an increase in cardiovascular mortality.
#sulfonylureas #antidiabetic #pharmacologymadeeasy #clinicalpharmacology #pharmacologylectures #pharmacybyasim

Chapters:
0:00 - sulfonylureas pharmacology (clinical pharmacology lecture)
0:16 - antidiabetic drugs pharmacology
0:32 - sulfonylureas mechanism of action
1:01 - sulfonylureas pharmacokinetics
1:32 - sulfonylureas side effects (sulfonylureas adverse effects)
1:40 - sulfonylureas contraindications
2:02 - sulfonylureas clinical pharmacology (clinical pearls)

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"Content is For Informational & Education Purpose Only, Creamed From Various Authentic Books of Pharmacy & Medicine. The Video Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition."