After the discovery of stem cells, we started isolating them and culturing them in the lab to make thousands and millions of them. One treatment is to directly inject those stem cells to the site of injury, which we call free cell transplantation. But it doesn't a very efficient treatment. Because most of the stem cells that we are going to inject are going to be lost during the procedure. Moreover, many of them don't know what they should do after that. To overcome this, we make a temporary structure called a "scaffold" to support the stem cells. It provides physical and chemical cues for our stem cells to proliferate and differentiate into more specified cells. Therefore, the properties of the scaffold are crucial. So, in this video, I will explain some of those properties.

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In this channel I'm using a number system for my references, which you can see the number in the left corner of my video. So, you can download the references file in here and use articles if you wanna gather more information and learn more.

References file:
https://drive.google.com/file/d/1audL...


In attributions file you can find all the Creative Commons licensees and materials that I used in this video.
Attributions file:
https://drive.google.com/file/d/1netb...

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1. The musics in this video is composed by amazing @ScottBuckley
make sure you check him out:
   / musicbyscottb  
2. I used some stock footage from these channels which is great. Check them out in:
   • Doctor Stock Footages - Doctors Free ...  
https://www.videezy.com
The rest you can find in attributions file.
3. the first scene derive from this channel:
   / goldeneagleloghomeswisconsinrapids  
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Timestamps:
00:00 Definition of extracellular matrix (ECM) and biomaterials
02:40 Stem cells transplantation and its problem
04:08 The relationship between stem cells and scaffold
04:50 Biomaterial source
05:28 Hydrophilicity
05:00 Porosity
07:00 Mechanical properties
08:00 Surface topography

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#TDIITD #Biomaterials #Tissueengineering