Experts discuss recommended treatment options for endometrial cancer and uterine sarcoma, side effects of treatment and survivorship, and finding and using supportive care and patient and caregiver resources.

Topics Discussed
00:00 Introduction
02:05 Overview of endometrial cancer and uterine sarcoma treatment
02:48 Epidemiology of uterine cancer
04:06 Endometrial cancer versus uterine sarcoma
05:31 Histology and grade of the cancer
07:35 Molecular classification
11:44 Genetic Testing
13:32 Staging
14:49 Surgery
17:20 Radiation treatment
18:17 Systemic treatment
19:32 Chemotherapy
20:14 Immunotherapy
21:06 Chemotherapy in combination with immunotherapy
22:15 Second-line therapy
22:44 Clinical trials
23:48 Factors that determine treatment
24:42 What to expect on your treatment day
25:47 First-line therapies for endometrial cancer and side effects
33:47 First-line therapies for uterine sarcoma and side effects
37:33 Radiation side effects
39:37 Toxicity management tip sheet and survivorship concerns
40:28 Patient advocate story
43:01 Things to consider after diagnosis: Fear
45:27 Things to consider after diagnosis: Facts, Faith, and Finances
46:50 Things to consider after diagnosis: Friends and family
48:02 Survivorship

Q&A Session
49:23 What is the role of trastuzumab (Herceptin) for HER2+ endometrial cancer?
50:43 Can you use the hair-growing drug minoxidil while chemo is still underway?
51:28 Can you provide the suggested protocol for peripheral neuropathy supplements?
52:12 When you have a recurrence, do they re-stage your cancer?
52:36 Can you take trastuzumab and another immunotherapy, and is there a preferred option?
53:38 When one sentinel lymph node is cancerous is there any way to tell if others are?
54:05 Do you have any suggestions for addressing chemotherapy-induced brain fog?
54:59 Is serious cancer treated the same as sarcoma?
55:09 Which occurs more frequently: uterine sarcoma or endometrial carcinosarcoma?
55:33 How are patient preferences incorporated into care decisions?
56:22 Should you continue neuropathy meds after treatment?
56:38 What is the role of neoantigen MRNA therapy?
57:06 What can be done to deal with muscle and joint pain?
57:44 What is the role of CDK4/6 inhibitors?
58:16 How does trastuzumab work differently than dostarlimab?
59:04 In endometrial carcinosarcoma recurrence, should there be new histology?
59:35 Will there be increased research into uterine sarcomas?
1:00:17 How can I help my relative to be active when they are tired or if they have lymphedema?
1:01:37 Does a hysteroscopy allow a doctor to find uterine sarcoma?
1:02:54 What type of cancer could you be suspectable to after treatment for endometrial cancer?
1:02:58 Does a Pap diagnose endometrial cancer?
1:03:26 How often should you have a PET scan after treatment?
1:04:25 What is the best radiation treatment technique?
1:05:10 Will there be more research to identify mutations for individualized therapy?
1:06:07 Why isn't lymphedema or pelvic floor therapy covered by insurance?
1:07:20 Conclusion

The Patient Webinar on Uterine Cancer occurred in December 2023. This program was created in conjunction with the NCCN Guidelines for Patients® for Uterine Cancer: https://www.nccn.org/patientresources...

The NCCN Guidelines for Patients are available to read and download for free online and via the NCCN Patient Guides for Cancer mobile app. Printed editions can be ordered from Amazon.com for a small fee.

NCCN Guidelines for Patients DO NOT replace the expertise and clinical judgment of the clinician.

Supporters:
This webinar is supported through the NCCN Foundation and by a contribution from our corporate supporter, GSK.
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About NCCN Foundation®:
NCCN FOUNDATION® is a 501(c)3 organization founded by the National Comprehensive Cancer Network® (NCCN®)—a not-for-profit alliance of leading cancer centers devoted to patient care, research, and education—to empower people living with cancer and advance oncology innovation. For more information or to make a donation, visit http://www.nccn.org/patients/foundation
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About NCCN:
The National Comprehensive Cancer Network® (NCCN®) is a not-for-profit alliance of leading cancer centers devoted to patient care, research, and education. NCCN is dedicated to improving and facilitating quality, effective, equitable, and accessible cancer care so all patients can live better lives. Visit https://www.nccn.org/ for more information.

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