Gabapentin is approved by the FDA for three specific indications to prevent and control partial seizures, relieve nerve pain following shingles (post herpetic neuralgia), and to treat moderate to severe restless leg syndrome. Unfortunately, less than 1% of the prescriptions written for gabapentin are for the above listed FDA approvals. In fact, much of the off-label prescribing of gabapentin is done for the treatment of psychiatric and substance use disorders.

Time Stamps
Introduction: 00:00 to 01:12
FDA approved indication and how we got here: 01:13 to 04:10
Mechanism of Action: 04:11 to 05:11
Why the increase in off-label prescribing: 05:12 to 08:34
Gabapentin For Anxiety: 08:35 to 11:38
Gabapentin for Bipolar Disorder: 11:39 to 13:23
Gabapentin for Alcohol/cannabis use disorder: 13:24 to 18:50
Gabapentin and chronic lower back pain: 18:51 to 19:57
Adverse Effects: 19:58 to 20:18
Dosing Gabapentin: 20:19 to 21:44
Conclusion: 21:45 to 23:46

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