Plimoth Patuxet is a complex of living history museums in Plymouth, Massachusetts founded in 1947, formerly Plimoth Plantation. It replicates the original settlement of the Plymouth Colony established in the 17th century by the English colonists who became known as the Pilgrims. They were among the first people who emigrated to America to seek religious separation from the Church of England. It is a not-for-profit museum supported by administrations, contributions, grants, and volunteers. The recreations are based upon a wide variety of first-hand and second-hand records, accounts, articles, and period paintings and artifacts, and the museum conducts ongoing research and scholarship, including historical archaeological excavation and curation locally and abroad.

In the English Village section of the museum, trained first-person ("historical") interpreters speak, act, and dress appropriately for the period, interacting with visitors by answering questions, discussing their lives and viewpoints, and participating in tasks such as cooking, planting, and animal husbandry. Third-person ("modern") interpreters answer guests' questions that the first-person interpreters cannot. The English Village represents the year 1627 through most of the museum season (which lasts from early April to late November), depicting day-to-day life and seasonal activities. In November, the English Village typically represents the year 1621, which is the year of the first Thanksgiving to take place in Plymouth Colony.

Henry Hornblower II started the museum in 1947 with help and support from friends, family, and business associates as two English cottages and a fort on Plymouth's waterfront. Since then, the museum has grown to include a Mayflower II replica (1957), the English Village (1959), the Wampanoag Homesite (1973), the Hornblower Visitor Center (1987), the Craft Center (1992), the Maxwell and Nye Barns (1994), and the Plimoth Grist Mill (2013). Alongside the settlement is a recreation of a Wampanoag home site, where Indians from a variety of tribes explain and demonstrate how the Wampanoags' ancestors lived.

The museum grounds at Plimoth Patuxet also include Nye Barn where historical breeds of livestock are kept, a crafts center where many objects are created for use in the village exhibits, a cinema where educational videos are shown, a Colonial Education site for youth and adult groups, and a visitors' center with indoor exhibits and educational programs. The two houses on the Colonial Education site were built for the PBS show Colonial House, which was filmed in Maine. Following the filming, the museum disassembled the houses and reconstructed them at on their current site. The roof of the Cooke House was destroyed by a fire from a fireplace on November 19, 2011, and the building had to be demolished.

Mayflower II is docked near Plymouth Rock and is also under the care of the museum. Museum employees in modern dress interpret history to guests from a third-person perspective.