Though it requires a living host in order to survive, the Venom symbiote has been shown to be adept at fending for itself independent of a host. The symbiote is capable of shapeshifting abilities, including the ability to form spikes or expand its size, as well as mimic the appearance of other humanoids after it has obtained a host. The organism can additionally use its shape-shifting abilities to conceal itself by altering its coloration or by becoming completely invisible. It also contains a small "dimensional aperture", allowing its hosts to carry items without adding mass to the costume. The symbiote also exhibits telepathic abilities, primarily when it needs to communicate with its host. Because of its contact with Spider-Man, the symbiote grants all of its subsequent hosts that hero's powers and cannot be detected by his spider-sense. As Spider-Man's fighting style is partly dependent on his spider-sense, his effectiveness was somewhat hampered when he battled Eddie Brock. Retaining its memory from the time it was bonded with Spider-Man, Venom is also capable of producing webbing similar to Spider-Man's own variety created from itself.

List of games:

1. The Amazing Spider-Man. GB (1990)
2. Spider-Man vs. The Kingpin. Sega Genesis (1991)
3. Spider-Man: The Video Game (1991)
4. Spider-Man vs. The Kingpin. Sega CD (1993)
5. Spider-Man and Venom: Maximum Carnage (1994)
6. The Amazing Spider-Man: Lethal Foes (1995)
7. Venom/Spider-Man: Separation Anxiety (1995)
8. Spider-Man: The Animated Series (1995)
9. Marvel vs. Capcom: Clash of Super Heroes (1998)
10. Marvel vs. Capcom 2: New Age of Heroes (2000)
11. Spider-Man (2000)
12. Spider-Man. GBC (2000)
13. Venom's Vindication (2004)
14. Ultimate Spider-Man. PC, PS2, Xbox (2005)
15. Ultimate Spider-Man. GBA (2005)
16. Ultimate Spider-Man. DS (2005)
17. Marvel Nemesis: Rise of the Imperfects. PS2, Xbox (2005)
18. Marvel Nemesis: Rise of the Imperfects. PSP (2005)
19. Marvel: Ultimate Alliance (2006)
20. Spider-Man 3. PC, PS3, X360 (2007)
21. Spider-Man 3. PS2, PSP, Wii (2007)
22. Spider-Man 3. DS (2007)
23. Spider-Man 3. GBA (2007)
24. Spider-Man 3. Java (2007)
25. Spider-Man: Friend or Foe (2007)
26. Spider-Man: Web of Shadows. PC, PS3, X360 (2008)
27. Spider-Man: Web of Shadows. PS2, PSP (2008)
28. Marvel: Ultimate Alliance 2 (2009)
29. LittleBigPlanet. Marvel Costume Pack 3 (2010)
30. Ultimate Spider-Man: Total Mayhem (2010)
31. Marvel Pinball (2010)
32. Marvel Super Hero Squad Online (2011)
33. Marvel Avengers Alliance (2012)
34. The Amazing Spider-Man. Java (2012)
35. Marvel vs. Capcom Origins (2012)
36. Marvel: War of Heroes (2012)
37. Marvel Avengers: Battle for Earth (2012)
38. Marvel Heroes (2013)
39. Marvel Puzzle Quest (2013)
40. Lego Marvel Super Heroes (2013)
41. The Amazing Spider-Man 2. Mobile (2014)
42. Spider-Man: Ultimate Power (2014)
43. Spider-Man Unlimited (2014)
44. Disney Infinity: Marvel Super Heroes (2014)
45. Marvel Contest of Champions (2014)
46. Marvel: Future Fight (2015)
47. Disney Infinity 3.0 (2015)
48. Marvel Avengers Academy (2016)
49. Marvel Tsum Tsum (2016)
50. Marvel vs. Capcom: Infinite (2017)
51. Lego Marvel Super Heroes 2 (2017)
52. Marvel Strike Force (2018)
53. Marvel End Time Arena (2018)
54. Marvel's Spider-Man (2018)
55. Marvel Powers United VR (2018)
56. Marvel Ultimate Alliance 3: The Black Order (2019)
57. Marvel Super War (2019)
58. Marvel Duel (2020)
59. Marvel's Spider-Man: Miles Morales (2020)
60. Fortnite (2020)
61. Marvel's Spider-Man 2 (2023)