We’ve been told for decades that it's caused by a chemical imbalance and low serotonin levels.

It turns out that is SIMPLY NOT TRUE.

But if depression isn’t caused by a chemical imbalance, what IS the cause?

There’s no single answer because depression is a complex, multifactorial condition.

But one theory that has gained a lot of support amongst experts in the field is that INFLAMMATION is a primary driver of depression.

In this video, I share the latest research linking inflammation to depression, tell you the most common causes of inflammation, and give you some tips for how to reduce inflammation and stabilize your mood.

—
/ / RESEARCH & RELATED RESOURCES
› So depression is an inflammatory disease, but where does the inflammation come from?: https://bmcmedicine.biomedcentral.com...

› Immunological Evidence Supporting the Immune-Cytokine Model of Depression: http://www.cytokines-and-depression.c...

› Negative Immunoregulatory Effects of Antidepressants: Inhibition of Interferon-γ and Stimulation of Interleukin-10 Secretion: https://www.nature.com/articles/1395271

› Is Depression a Disease or a Symptom of Inflammation?: https://chriskresser.com/is-depressio...

› Obesity, inflammation and the immune system: https://pubmed.ncbi.nlm.nih.gov/22429...

› Evidence for prospective associations among depression and obesity in population-based studies: https://pubmed.ncbi.nlm.nih.gov/21414...

› Involvement of reactive oxygen intermediates in cyclooxygenase-2 expression induced by interleukin-1, tumor necrosis factor-alpha, and lipopolysaccharide: https://pubmed.ncbi.nlm.nih.gov/7706475/

› 99th Dahlem Conference on Infection, Inflammation and Chronic Inflammatory Disorders: Psycho-neuroimmunology and the intestinal microbiota: clinical observations and basic mechanisms: https://onlinelibrary.wiley.com/doi/1...

› Heal Your Gut, Heal Your Brain: https://chriskresser.com/heal-your-gu...

› Effects of a 1-year supplementation with cholecalciferol on interleukin-6, tumor necrosis factor-alpha and insulin resistance in overweight and obese subjects: https://pubmed.ncbi.nlm.nih.gov/22925...

› Impact of vitamin D supplementation on markers of inflammation in adults with cystic fibrosis hospitalized for a pulmonary exacerbation: https://pubmed.ncbi.nlm.nih.gov/22805...

› Dietary magnesium and C-reactive protein levels: https://pubmed.ncbi.nlm.nih.gov/15930...

› Zinc status is associated with inflammation, oxidative stress, lipid, and glucose metabolism: https://jps.biomedcentral.com/article...

› Zinc, Magnesium, Selenium and Depression: A Review of the Evidence, Potential Mechanisms and Implications: https://pubmed.ncbi.nlm.nih.gov/29747...

› Sleep Loss and Inflammation: https://www.ncbi.nlm.nih.gov/pmc/arti...

› Sleep and Depression: https://psycnet.apa.org/record/2006-1...

› How to Get Better Sleep:    • How to Get Better Sleep  

—
/ / SUBSCRIBE for more videos like this:    / @chriskresser  

—
/ / LETS CONNECT
› Instagram:   / chriskresser  

› Facebook:   / chriskresserlac  

› LinkedIn:   / chris-kresser-l.ac