MIT 6.874/6.802/20.390/20.490/HST.506 Spring 2021 Prof. Manolis Kellis
Guest Lecture: Joshua Welch
Deep Learning in the Life Sciences / Computational Systems Biology
Playlist:    • MIT Deep Learning in Life Sciences - ...  
Latest slides and course today: http://compbio.mit.edu/6874
Spring 2021 slides and materials: http://mit6874.github.io/

0:00 Introduction
2:27 Statistical tests
6:20 Dimensionality reduction
12:00 Principal component analysis
25:55 t-SNE
33:21 t-SNE parameters
38:42 Single-cell genomics
42:57 Metagenes
42:50 LIGER and integrative nonnegative matrix factorization
50:12 iNMF optimization
1:03:50 Online learning for iNMF
1:13:35 Integrating datasets with partially overlapping features
1:16:29 Combining VAEs and GANs to generate scRNA profiles